Research into Fibromyalgia has seen a growth spurt over the last                                                                         32 years but more is desperately needed.  There are such a                                                                              plethora of research articles that I can't possibly list all the studies                                                                        here (I am a person with Fibro with a background in law                                                                                enforcement so some of these reports are over my head).  Every                                                                          month I will list the two or three research studies that I                                                                                       find interesting.

2025

April

An association between poor oral health, oral microbiota, and pain identified in New Zealand women with central sensitisation disorders: a prospective clinical study

Sharon Erdrich, et. al.

Front. Pain Res., 08 April 2025

Sec. Pain Mechanisms

Volume 6 - 2025 | https://doi.org/10.3389/fpain.2025.1577193

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Abstract

The portal to the gastrointestinal tract is the oral cavity, with transient and permanent microbial residents. Oral pathogens are implicated in the aetiology of several chronic conditions. To date, the role of oral health and the oral microbiota in the aetiology of pain in sensitisation disorders have not been explored. Here, we examined associations between self-reported oral health, the oral microbiome, and various pain presentations in women.

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Cannabis or Cannabinoids for the Management of Chronic Noncancer Pain: Best Practice Advice From the American College of Physicians

Devan Kansagara, Kevin P. Hill, Jennifer Yost, et al. 

Cannabis or Cannabinoids for the Management of Chronic Noncancer Pain: Best Practice Advice From the American College of Physicians. 

Ann Intern Med.

 [Epub 4 April 2025]. doi:10.7326/ANNALS-24-03319

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Abstract

The American College of Physicians’ Population Health and Medical Science Committee (PHMSC) developed this best practice advice to inform clinicians about what is currently known about the benefits and harms of cannabis or cannabinoids in the management of chronic noncancer pain and to provide advice for clinicians counseling patients seeking this therapy..

 

Februrary

Decoding the connection: unraveling the role of gut microbiome in fibromyalgia. 

Minerbi, Amira,b,c,*; Khoutorsky, Arkadyc,d,e; Shir, Yoramd,f. 
PAIN Reports 
10(1):p e1224, February 2025. | DOI: 10.1097/PR9.0000000000001224

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Abstract

The gut microbiome is emerging as a critical player in the pathophysiology of fibromyalgia, offering mechanistic insights as well as potential diagnostic and therapeutic applications.  The article explores the intricate relationship between the gut microbiome and fibromyalgia, focusing on emerging research that suggests a potential link between them, and highlighting the implications for future therapeutic interventions..

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